The first Southpark episode was created via stop motion using construction paper cutouts

It takes 5 days to create a Southpark episode

Southpark character Butters Stough is based on the show's animation director Eric Stough

Mr. Mackey is based on Trey Parker's school counselor Mr. Lackey

When George Clooney requested a guest starring role in Southpark, he was offered a role as Stan's dog. He accepted, providing his best barking dog impersonation

Casa Bonita from South Park is a real restaurant in Denver